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Contents
Common use
Reglan (metoclopramide) is a gastrointestinal prokinetic agent that helps manage nausea, vomiting, heartburn due to GERD, and delayed gastric emptying (gastroparesis), especially in individuals with diabetes.
It promotes faster stomach emptying by enhancing muscle contractions in the digestive tract and blocks dopamine receptors in the brain that trigger nausea.
Dosage and direction
Follow your doctor's instructions carefully when taking Reglan. A typical dosage is 10 mg taken up to four times per day, usually 30 minutes before meals and at bedtime. The treatment duration should not exceed 12 weeks unless your healthcare provider advises otherwise.
The tablets should be swallowed whole with water and can be taken with or without food, depending on how your stomach tolerates it.
Precautions
Before beginning treatment with Reglan, notify your healthcare provider if you have or have had:
• Mental health conditions such as anxiety, depression, or psychosis
• Parkinson's disease or other movement disorders
• Impaired kidney or liver function
• Hypertension (high blood pressure)
Use caution if you're elderly, as the risk of movement-related side effects is higher. Alcohol should be avoided, as it may intensify drowsiness or dizziness.
Contraindications
Do not take Reglan if you:
• Have a seizure disorder such as epilepsy
• Are allergic to metoclopramide or its components
• Suffer from gastrointestinal bleeding, perforation, or obstruction
• Have been diagnosed with pheochromocytoma (a rare adrenal tumor)
Its use in children is generally not recommended unless specifically directed by a pediatric specialist.
Possible side effects
Frequent side effects may include:
• Drowsiness or fatigue
• Restlessness or agitation
• Diarrhea
Less common but serious side effects:
• Tardive dyskinesia (involuntary facial or limb movements)
• Depression, suicidal ideation
• Hallucinations or mental confusion
Seek urgent care if you experience muscle rigidity, high fever, or trouble breathing - these could indicate a severe reaction.
Drug interactions
Metoclopramide may interact with several medications, such as:
• Antidepressants and antipsychotics
• Opioid-based pain relievers
• Sedatives or sleep aids
• Digoxin and insulin
Always provide your doctor or pharmacist with a full list of medications and supplements you are taking to prevent harmful interactions.
Missed dose
If you forget a dose, take it as soon as possible. If the next scheduled dose is close, skip the missed one. Do not double the dose to make up for the forgotten tablet.
Overdose
Symptoms of an overdose might include extreme sleepiness, convulsions, muscle spasms, or severe confusion. In case of overdose, contact emergency medical help or call poison control immediately.
Storage
Keep Reglan stored at room temperature (68°-77°;F / 20°-25°;C). Protect it from heat, moisture, and direct light. Keep out of reach of children and pets.
U.S. Sale and Prescription Policy
In the United States, Reglan is a prescription-only medication, approved by the FDA for specific gastrointestinal conditions. It is dispensed legally through licensed pharmacies under a physician's supervision.
Due to the potential for neurological side effects such as tardive dyskinesia, usage is typically limited to short-term treatment unless otherwise warranted.
However, Home Care Pharmacy offers a special service allowing eligible individuals to purchase Reglan without a traditional prescription, depending on their location and health screening. This access is provided through licensed professionals in regions where pharmacy-based prescribing is permitted.
This model ensures safe access to treatment while still respecting medical oversight and individual safety.
Disclaimer
This content is intended for educational purposes and does not replace medical consultation. Always seek advice from a licensed physician or pharmacist before starting or modifying any treatment. The authors are not liable for misuse or misinterpretation of the information provided above.