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Contents
Common use
Allopurinol is a medication from the xanthine oxidase inhibitor class, commonly prescribed to reduce uric acid levels in both the blood and urine. It is typically used for managing gout, recurrent kidney stones, and elevated uric acid caused by cancer treatments such as chemotherapy.
This drug is not meant to alleviate acute gout attacks directly but is effective for preventing future flare-ups by maintaining stable uric acid concentrations.
Dosage and direction
Allopurinol is taken orally, typically once or twice a day, preferably after meals and with a full glass of water. The exact dosage depends on your health condition and response to therapy.
Adequate hydration is important during treatment. Do not stop taking the medication without medical advice, even if symptoms improve. It may take several weeks to feel the full benefit.
Your physician may initiate treatment with a low dose to minimize potential side effects, gradually increasing it over time.
Precautions
Discuss your full medical history with your healthcare provider before starting Allopurinol, especially if you have:
Liver or kidney impairment
Hypertension (high blood pressure)
Diabetes mellitus
Pregnant or breastfeeding patients should use this medicine only under medical supervision.
People of Asian descent may be at higher risk for serious skin reactions if they carry the HLA-B5801 gene. Genetic screening may be recommended.
Contraindications
Do not use Allopurinol if you are hypersensitive to this drug or similar agents. It is not suitable for use during an active gout attack.
Avoid excessive intake of alcohol or purine-rich foods (such as red meat or shellfish), which may counteract the medication's effectiveness.
Possible side effects
Frequently reported side effects include:
Upset stomach
Diarrhea
Mild skin rash
Drowsiness
Rare but serious reactions may include:
Stevens-Johnson syndrome
Changes in liver enzymes
Blood in urine
Numbness or tingling in limbs
Promptly contact a doctor if you develop symptoms such as severe rash, fever, or changes in urination.
Drug interactions
Allopurinol may interact with several medications, such as:
Azathioprine or mercaptopurine (immunosuppressants)
Penicillin-type antibiotics (e.g., amoxicillin)
Warfarin or other anticoagulants
Always disclose your current medications and supplements to your doctor before starting treatment.
Missed dose
If you miss a dose, take it as soon as you remember. If your next dose is near, skip the missed one and continue your usual schedule. Do not take two doses at once.
Overdose
Symptoms of overdose may include severe nausea, dizziness, or serious allergic skin reactions. Immediate medical attention is strongly advised in such cases.
Storage
Keep Allopurinol stored at controlled room temperature (68°-77°;F or 20°-25°;C). Protect the medication from moisture, heat, and direct sunlight. Keep the container tightly sealed and away from children or pets.
U.S. Sale and Prescription Policy
In the United States, Allopurinol is an FDA-authorized prescription drug, usually prescribed for chronic gout and uric acid control. Traditional sales require a valid doctor's prescription.
However, Home Care Pharmacy offers eligible patients a safe option to obtain Allopurinol without a prescription, following pharmacist-led assessment and screening in accordance with applicable healthcare guidelines. This option ensures proper usage while easing access for individuals with ongoing uric acid issues.
Be cautious when buying online. Only use certified, U.S.-based pharmacies to avoid counterfeit or unsafe medication.
Disclaimer
This content is provided for general information only and does not substitute professional medical advice. Always follow guidance from a licensed physician or pharmacist before beginning, altering, or discontinuing any treatment.