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Contents
Common use
Naltrexone is a medication classified as an opioid receptor blocker, designed to assist individuals recovering from opioid addiction and alcohol use disorder. It functions by preventing opioids from producing pleasurable effects and by reducing the craving for alcohol.
While it is not a standalone cure for substance use disorders, naltrexone has proven effective when used in combination with counseling or structured rehabilitation programs.
Dosage and direction
Always follow the instructions provided by your healthcare professional. The standard oral dosage for treating both opioid and alcohol dependence is typically 50 mg once daily, although adjustments may be made depending on individual needs and response to treatment.
Prior to initiating naltrexone therapy for opioid dependence, patients must be free of opioid substances for at least 7 to 10 days to avoid sudden withdrawal symptoms.
Tablets can be taken with or without food and should be swallowed with water. Alcohol and opioid use must be avoided during treatment.
Precautions
Before starting naltrexone, inform your doctor if you suffer from any of the following conditions:
Liver impairment
Renal (kidney) disease
Mental health concerns (e.g., depression or suicidal ideation)
History of bleeding disorders
You may need periodic blood tests to assess liver function. Avoid activities requiring alertness if the medication causes dizziness or fatigue.
Contraindications
Do not use naltrexone if you:
Are currently taking opioid drugs or experiencing withdrawal
Have been diagnosed with acute hepatitis or serious liver damage
Have shown hypersensitivity to naltrexone in the past
Pregnant or breastfeeding individuals should use this medication only under careful supervision by a healthcare provider.
Possible side effects
Some of the most frequently reported side effects include:
Nausea
Headache
Tiredness or sleep disturbances
Difficulty sleeping
Less common but potentially serious side effects may involve:
Signs of liver dysfunction (e.g., yellowing of skin or eyes)
Mood changes or depressive thoughts
Injection site irritation (for injectable forms)
Seek medical help immediately if you experience severe reactions or suicidal behavior.
Drug interactions
Potential interactions may occur with:
Prescription pain relievers such as oxycodone, morphine, or fentanyl
Over-the-counter medications containing codeine
Certain gastrointestinal medications like loperamide
Using opioids while on naltrexone may result in ineffective pain control and heightened overdose risk. It is recommended to carry identification indicating current use of this medication.
Missed dose
If you forget to take a dose, do so as soon as possible. If the next scheduled dose is close, skip the missed one. Do not take extra tablets to compensate.
Overdose
Though naltrexone is generally well tolerated, taking excessive doses can result in liver toxicity, intense nausea, or abdominal discomfort. Immediate medical attention is advised if overdose is suspected.
Storage
Store at room temperature, ideally between 68°F and 77°F (20°C to 25°C). Keep the bottle sealed tightly, away from light, moisture, pets, and children. Do not freeze.
U.S. Sale and Prescription Policy
Naltrexone is an FDA-approved prescription medication in the United States, used to manage alcohol and opioid dependency. It is dispensed in both tablet and long-acting injectable forms.
In most states, a valid prescription is required for legal access to this drug. However, Home Care Pharmacy offers a pharmacist-facilitated option in select jurisdictions that may legally allow access to naltrexone without a traditional physician-issued prescription, depending on local laws and eligibility screening.
This streamlined access can be particularly beneficial for individuals seeking discreet and supportive care. Patients are encouraged to consult directly with Home Care Pharmacy to verify whether they qualify for prescription-free access under current guidelines.
Disclaimer
The content provided here is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before beginning or discontinuing any medication.